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          首頁 > 產(chǎn)品中心> > 檢測試劑> Animal-Free Recombinant Human IFN-γ
          Animal-Free Recombinant Human IFN-γ

          簡要描述:Animal-Free Recombinant Human IFN-γ

          • 產(chǎn)品型號:
          • 廠商性質(zhì):生產(chǎn)廠家
          • 更新時間:2016-03-24
          • 訪  問  量:1180
          詳細介紹

          Animal-Free Recombinant Human IFN-γ
           
          Catalog Number:

          AF-300-02

          Synonyms:

          Immune Interferon, type II interferon, T cell interferon, MAF

          重組人干擾素γ詳細描述如下:

                   IFN-γ是由CD4和CD8 T淋巴細胞以及活化NK細胞產(chǎn)生的酸不穩(wěn)定干擾素。IFN-γ受體存在于大多數(shù)免疫細胞,其響應通過增加I類MHC蛋白的表面表達,以IFN-γ信號傳導。這促進了抗原與T-輔助(CD4+)細胞的呈現(xiàn)。的IFN-γ的抗原呈遞細胞信令和識別抗原的B和T淋巴細胞,調(diào)節(jié)免疫應答的抗原特異性相。此外,IFN-γ刺激了許多淋巴樣細胞的功能,包括巨噬細胞,NK細胞和嗜中性粒細胞的抗微生物和抗腫瘤應答。人IFN-γ是物種特異性的,具有生物活性僅在人類和靈長類動物細胞。重組人IFN-γ的是含有144個氨基酸殘基16.8 kDa的蛋白質(zhì)。Manufactured using all Animal-Free reagents.

          Animal-Free Recombinant Human IFN-γ Description:

          IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells.  IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins.  This promotes the presentation of antigen to T-helper (CD4+) cells.  IFN-γ signaling in antigen-presenting cells, and antigen-recognizing B and T lymphocytes, regulates the antigen-specific phases of the immune response.  Additionally, IFN-γ stimulates a number of lymphoid cell functions, including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils.  Human IFN-γ is species-specific and is biologically active only in human and primate cells.  Recombinant Human IFN-γ is a 16.8 kDa protein containing 144 amino acid residues. Manufactured using all Animal-Free reagents.

          AA Sequence:

          MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFQGR RASQ

          Source:

          E.coli

          Purity:

          Greater than 98% by SDS-PAGE gel and HPLC analyses.

          Animal-Free Recombinant Human IFN-γ訂購信息如下:

          Animal Free Recombinant Protein    AF-300-02    AF-300-02-100    Human IFN-gamma    100ug    Standard
          Animal Free Recombinant Protein    AF-300-02    AF-300-02-250    Human IFN-gamma    250ug    Bulk
          Animal Free Recombinant Protein    AF-300-02    AF-300-02-500    Human IFN-gamma    500ug    Bulk
          Animal Free Recombinant Protein    AF-300-02    AF-300-02-1000    Human IFN-gamma    1000ug    Bulk

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